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PDBsum entry 5c4l
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PDB id:
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Transferase
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Title:
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Conformational alternate of sisomicin in complex with aph(2")-iva
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Structure:
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Aph(2'')-id. Chain: a, b. Engineered: yes. Mutation: yes
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Source:
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Enterococcus casseliflavus. Organism_taxid: 37734. Gene: aph(2'')-id. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.35Å
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R-factor:
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0.230
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R-free:
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0.278
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Authors:
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E.Kaplan,J.F.Guichou,K.Berrou,L.Chaloin,N.Leban,P.Lallemand,T.Barman, E.H.Serpersu,C.Lionne
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Key ref:
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E.Kaplan
et al.
(2016).
Aminoglycoside binding and catalysis specificity of aminoglycoside 2″-phosphotransferase IVa: A thermodynamic, structural and kinetic study.
Biochim Biophys Acta,
1860,
802-813.
PubMed id:
DOI:
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Date:
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18-Jun-15
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Release date:
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03-Feb-16
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PROCHECK
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Headers
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References
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O68183
(O68183_ENTCA) -
APH(2'')-Id from Enterococcus casseliflavus
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Seq:
Struc:
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301 a.a.
297 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 2 residue positions (black
crosses)
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DOI no:
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Biochim Biophys Acta
1860:802-813
(2016)
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PubMed id:
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Aminoglycoside binding and catalysis specificity of aminoglycoside 2″-phosphotransferase IVa: A thermodynamic, structural and kinetic study.
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E.Kaplan,
J.F.Guichou,
L.Chaloin,
S.Kunzelmann,
N.Leban,
E.H.Serpersu,
C.Lionne.
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ABSTRACT
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Links
