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PDBsum entry 5awm
Go to PDB code: 
protein ligands metals links
Transferase PDB id
5awm

 

 

 

 

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JSmol PyMol  
Contents
Protein chain
345 a.a.
Ligands
ANP
Metals
_MG ×2
Waters ×143
PDB id:
5awm
Name: Transferase
Title: The crystal structure of jnk from drosophila melanogaster reveals an evolutionarily conserved topology with that of mammalian jnk proteins.
Structure: Stress-activated protein kinase jnk. Chain: a. Synonym: djnk,protein basket. Engineered: yes
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: bsk, jnk, cg5680. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.79Å     R-factor:   0.179     R-free:   0.220
Authors: P.Boonserm
Key ref: S.Chimnaronk et al. (2015). The crystal structure of JNK from Drosophila melanogaster reveals an evolutionarily conserved topology with that of mammalian JNK proteins. Bmc Struct Biol, 15, 17. PubMed id: 26377800 DOI: 10.1186/s12900-015-0045-1
Date:
06-Jul-15     Release date:   05-Aug-15    
Supersedes: 4m3a
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P92208  (JNK_DROME) -  Stress-activated protein kinase JNK from Drosophila melanogaster
Seq:
Struc: 		372 a.a.
345 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.24  - mitogen-activated protein kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction:
1. L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
2. L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
L-seryl-[protein]
 + ATP
 = O-phospho-L-seryl-[protein]
 +
ADP
Bound ligand (Het Group name = ANP)
matches with 81.25% similarity 		+ H(+)
L-threonyl-[protein]
 + ATP
 = O-phospho-L-threonyl-[protein]
 +
ADP
Bound ligand (Het Group name = ANP)
matches with 81.25% similarity 		+ H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

 
    reference    
 
 
DOI no: 10.1186/s12900-015-0045-1 Bmc Struct Biol 15:17 (2015)
PubMed id: 26377800  
 
 
The crystal structure of JNK from Drosophila melanogaster reveals an evolutionarily conserved topology with that of mammalian JNK proteins.
S.Chimnaronk, J.Sitthiroongruang, K.Srisucharitpanit, M.Srisaisup, A.J.Ketterman, P.Boonserm.
 
  ABSTRACT  
 
No abstract given.

 

 

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