PDBsum entry 5ezu

Viral protein

PDB id: 5ezu

Contents

Protein chains

76 a.a.

67 a.a.

Ligands

MYR

Waters ×57

PDB id:

5ezu

Name:

Viral protein

Title:

Crystal structure of the n-terminal domain of vaccinia virus immunomodulator a46 in complex with myristic acid.

Structure:

Protein a46. Chain: a, b. Engineered: yes

Source:

Vaccinia virus (strain western reserve). Vacv. Organism_taxid: 10254. Gene: vacwr172, a46r. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.55Å R-factor: 0.202 R-free: 0.242

Authors:

S.Fedosyuk,G.A.Bezerra,M.Sammito,I.Uson,T.Skern

Key ref:

S.Fedosyuk et al. (2016). Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins. Plos Pathog, 12, e1006079. PubMed id: 27973613 DOI: 10.1371/journal.ppat.1006079

Date:

26-Nov-15 Release date: 30-Nov-16

Protein chain

P26672  (A46_VACCW) -  Protein OPG176 from Vaccinia virus (strain Western Reserve)

Seq: 240 a.a.

Struc: 76 a.a.

Protein chain

P26672  (A46_VACCW) -  Protein OPG176 from Vaccinia virus (strain Western Reserve)

Seq: 240 a.a.

Struc: 67 a.a.

Enzyme reactions

• Enzyme class: Chains A, B: E.C.?

DOI no: 10.1371/journal.ppat.1006079

Plos Pathog 12:e1006079 (2016)

PubMed id: 27973613

Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins.

S.Fedosyuk, G.A.Bezerra, K.Radakovics, T.K.Smith, M.Sammito, N.Bobik, A.Round, L.F.Ten Eyck, K.Djinović-Carugo, I.Usón, T.Skern.

ABSTRACT

No abstract given.