PDBsum entry 5eq4

Sugar binding protein

PDB id: 5eq4

Contents

Protein chains

188 a.a.

195 a.a.

Ligands

ACT ×2

Metals

_CA ×9

Waters ×666

PDB id:

5eq4

Name:

Sugar binding protein

Title:

Crystal structure of the srpa adhesin r347e mutant from streptococcus sanguinis

Structure:

Platelet-binding glycoprotein. Chain: a, b, c, d. Engineered: yes. Mutation: yes

Source:

Streptococcus sanguinis. Organism_taxid: 388919. Strain: sk36. Gene: srpa, ssa_0829. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.30Å R-factor: 0.205 R-free: 0.257

Authors:

L.V.Loukachevitch,K.M.Mcculloch,K.R.Vann,Z.Wawrzak,S.Anderson, T.M.Iverson

Key ref:

B.A.Bensing et al. (2016). Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin. J Biol Chem, 291, 7230-7240. PubMed id: 26833566 DOI: 10.1074/jbc.M115.701425

Date:

12-Nov-15 Release date: 27-Jan-16

Protein chain

A3CM52  (A3CM52_STRSV) -  Platelet-binding glycoprotein from Streptococcus sanguinis (strain SK36)

Seq: 1625 a.a.

Struc: 188 a.a.*

Protein chains

A3CM52  (A3CM52_STRSV) -  Platelet-binding glycoprotein from Streptococcus sanguinis (strain SK36)

Seq: 1625 a.a.

Struc: 195 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

DOI no: 10.1074/jbc.M115.701425

J Biol Chem 291:7230-7240 (2016)

PubMed id: 26833566

Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin.

B.A.Bensing, L.V.Loukachevitch, K.M.McCulloch, H.Yu, K.R.Vann, Z.Wawrzak, S.Anderson, X.Chen, P.M.Sullam, T.M.Iverson.

ABSTRACT

No abstract given.