PDBsum entry 5ekt

Hydrolase

PDB id: 5ekt

Contents

Protein chains

197 a.a.

Ligands

FLC

Waters ×383

PDB id:

5ekt

Name:

Hydrolase

Title:

Crystal structure of mutant-k146a of peptidyl-tRNA hydrolase from vibrio cholerae at 1.63a resolution.

Structure:

Peptidyl-tRNA hydrolase. Chain: a, b. Synonym: pth. Engineered: yes. Mutation: yes

Source:

Vibrio cholerae o1 biovar el tor str. N16961. Organism_taxid: 243277. Strain: atcc 39315 / el tor inaba n16961. Atcc: 39315. Gene: pth, vc_2184. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.63Å R-factor: 0.189 R-free: 0.228

Authors:

S.Shahid,A.Kabr,R.K.Pal,A.Arora

Key ref:

S.Shahid et al. Crystal structure of mutant-K146a of peptidyl-Trna hy from vibrio cholerae at 1.63a resolution.. To be published, .

Date:

04-Nov-15 Release date: 09-Nov-16

Protein chains

Q9KQ21  (PTH_VIBCH) -  Peptidyl-tRNA hydrolase from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

Seq: 196 a.a.

Struc: 197 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.1.1.29 - peptidyl-tRNA hydrolase.
• Reaction: an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site