PDBsum entry 5e6i

Immune system

PDB id: 5e6i

Contents

Protein chains

201 a.a.

239 a.a.

261 a.a.

96 a.a.

97 a.a.

268 a.a.

191 a.a.

Ligands

GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU ×4

PDB id:

5e6i

Name:

Immune system

Title:

Crystal structure of tcr pf8 in complex with flu mp(58-66) epitope presented by hla-a2

Structure:

Tcr alpha chain,human nkt tcr alpha chain. Chain: g, a, f, p. Synonym: human nkt tcr beta chain. Engineered: yes. T-cell receptor beta-2 chain c region. Chain: h, b, l, q. Engineered: yes. Hla class i histocompatibility antigen, a-2 alpha chain. Chain: i, c, m, r.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: b2m, hdcma22p. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: trbc2. Gene: hla-a, hlaa. Gene: b2m, cdabp0092, hdcma22p.

Resolution:

4.00Å R-factor: 0.263 R-free: 0.338

Authors:

M.Gao,R.Mariuzza

Date:

09-Oct-15 Release date: 19-Oct-16

Protein chains

K7N5M3  (K7N5M3_HUMAN) -  Human nkt tcr alpha chain from Homo sapiens

Seq: 220 a.a.

Struc: 201 a.a.*

Protein chains

No UniProt id for this chain

Struc: 239 a.a.

Protein chains

P04439  (1A03_HUMAN) -  HLA class I histocompatibility antigen, A alpha chain from Homo sapiens

Seq: 365 a.a.

Struc: 261 a.a.*

Protein chains

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 96 a.a.

Protein chains

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 97 a.a.

Protein chain

P04439  (1A03_HUMAN) -  HLA class I histocompatibility antigen, A alpha chain from Homo sapiens

Seq: 365 a.a.

Struc: 268 a.a.*

Protein chain

K7N5M3  (K7N5M3_HUMAN) -  Human nkt tcr alpha chain from Homo sapiens

Seq: 220 a.a.

Struc: 191 a.a.*

* PDB and UniProt seqs differ at 171 residue positions (black crosses)