PDBsum entry 5e5l

Transferase

PDB id: 5e5l

Contents

Protein chains

190 a.a.

200 a.a.

Waters ×358

PDB id:

5e5l

Name:

Transferase

Title:

Crystal structure of mycobacterium tuberculosis l,d-transpeptidase 1 at 1.89 angstrom

Structure:

L,d-transpeptidase 1. Chain: a, b, c, d. Fragment: residues 32-251. Synonym: ldt 1,ldt(mt1). Engineered: yes

Source:

Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: atcc 25618 / h37rv. Gene: ldta, rv0116c, rvbd_0116c, p425_00122. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.89Å R-factor: 0.214 R-free: 0.257

Authors:

P.Kumar,G.Lamichhane,S.L.Ginell

Key ref:

P.Kumar et al. (2017). Non-classical transpeptidases yield insight into new antibacterials. Nat Chem Biol, 13, 54-61. PubMed id: 27820797 DOI: 10.1038/nchembio.2237

Date:

08-Oct-15 Release date: 26-Oct-16

Protein chains

O53638  (LDT1_MYCTU) -  L,D-transpeptidase 1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Seq: 251 a.a.

Struc: 190 a.a.

Protein chain

O53638  (LDT1_MYCTU) -  L,D-transpeptidase 1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Seq: 251 a.a.

Struc: 200 a.a.

Enzyme reactions

• Enzyme class: Chains A, B, C, D: E.C.2.3.2.- - ?????

DOI no: 10.1038/nchembio.2237

Nat Chem Biol 13:54-61 (2017)

PubMed id: 27820797

Non-classical transpeptidases yield insight into new antibacterials.

P.Kumar, A.Kaushik, E.P.Lloyd, S.G.Li, R.Mattoo, N.C.Ammerman, D.T.Bell, A.L.Perryman, T.A.Zandi, S.Ekins, S.L.Ginell, C.A.Townsend, J.S.Freundlich, G.Lamichhane.

ABSTRACT

No abstract given.