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PDBsum entry 5dp2
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protein ligands links
Oxidoreductase PDB id
5dp2

 

 

 

 

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JSmol PyMol  
Contents
Protein chain
335 a.a.
Ligands
NAP
Waters ×558
PDB id:
5dp2
Name: Oxidoreductase
Title: Curf er cyclopropanase from curacin a biosynthetic pathway
Structure: Curf. Chain: a. Fragment: unp residues 273-611. Engineered: yes
Source: Lyngbya majuscula. Organism_taxid: 158786. Gene: curf. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
0.96Å     R-factor:   0.117     R-free:   0.131
Authors: D.Khare,J.L.Smith
Key ref: D.Khare et al. (2015). Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase. Structure, 23, 2213-2223. PubMed id: 26526850 DOI: 10.1016/j.str.2015.09.013
Date:
12-Sep-15     Release date:   18-Nov-15    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q6DNE7  (Q6DNE7_9CYAN) -  CurF from Lyngbya majuscula
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		3195 a.a.
335 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.35  - 3-hydroxyacyl-CoA dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: a (3S)-3-hydroxyacyl-CoA + NAD+ = a 3-oxoacyl-CoA + NADH + H+
(3S)-3-hydroxyacyl-CoA
 +
NAD(+)
Bound ligand (Het Group name = NAP)
matches with 91.67% similarity 		= 3-oxoacyl-CoA
 + NADH
 + H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

 
    reference    
 
 
DOI no: 10.1016/j.str.2015.09.013 Structure 23:2213-2223 (2015)
PubMed id: 26526850  
 
 
Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase.
D.Khare, W.A.Hale, A.Tripathi, L.Gu, D.H.Sherman, W.H.Gerwick, K.Håkansson, J.L.Smith.
 
  ABSTRACT  
 
No abstract given.

 

 

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