PDBsum entry 5axd

Hydrolase

PDB id: 5axd

Contents

Protein chains

429 a.a.

Ligands

NAD ×2

RBV ×2

Waters ×1073

PDB id:

5axd

Name:

Hydrolase

Title:

Crystal structure of mouse sahh complexed with ribavirin

Structure:

Adenosylhomocysteinase. Chain: a, c. Synonym: adohcyase,cubp,liver copper-binding protein,s-adenosyl-l- homocysteine hydrolase. Engineered: yes

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: ahcy. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.60Å R-factor: 0.159 R-free: 0.180

Authors:

Y.Kusakabe,M.Ishihara,N.Tanaka

Key ref:

Y.Kusakabe et al. Crystal structure of mouse sahh complexed with ribavi. To be published, .

Date:

24-Jul-15 Release date: 27-Jul-16

Protein chains

P50247  (SAHH_MOUSE) -  Adenosylhomocysteinase from Mus musculus

Seq: 432 a.a.

Struc: 429 a.a.

Enzyme reactions

• Enzyme class: E.C.3.13.2.1 - adenosylhomocysteinase.
• Reaction: S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine

S-adenosyl-L-homocysteine + H2O = L-homocysteine (Bound ligand (Het Group name = RBV) matches with 71.43% similarity) + adenosine

Molecule diagrams generated from .mol files obtained from the KEGG ftp site