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PDBsum entry 4zwm

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protein ligands Protein-protein interface(s) links
Transferase PDB id
4zwm

 

 

 

 

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Contents
Protein chains
421 a.a.
Ligands
PLP ×2
SO4 ×12
Waters ×171
PDB id:
4zwm
Name: Transferase
Title: 2.3 a resolution crystal structure of the ornithine aminotransferase from toxoplasma gondii me49
Structure: Ornithine aminotransferase, mitochondrial, putative. Chain: a, b. Engineered: yes
Source: Toxoplasma gondii me49. Organism_taxid: 508771. Gene: tgme49_269110. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.31Å     R-factor:   0.190     R-free:   0.258
Authors: E.V.Filippova,G.Minasov,K.Flores,H.Van Le,R.B.Silverman,R.Mcleod, W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid)
Key ref: E.V.Filippova et al. 2.3 a resolution crystal structure of the ornithine aminotransferase from toxoplasma gondii me49. To be published, .
Date:
19-May-15     Release date:   03-Jun-15    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
S8EY38  (S8EY38_TOXGM) -  Ornithine aminotransferase from Toxoplasma gondii (strain ATCC 50611 / Me49)
Seq:
Struc:
441 a.a.
421 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.6.1.13  - ornithine aminotransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid
2-oxocarboxylate
+ L-ornithine
= L-glutamate 5-semialdehyde
+ L-alpha-amino acid
      Cofactor: Pyridoxal 5'-phosphate
Pyridoxal 5'-phosphate
Bound ligand (Het Group name = PLP) matches with 93.75% similarity
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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