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PDBsum entry 4zwl
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Oxidoreductase
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PDB id
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4zwl
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PDB id:
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| Name: |
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Oxidoreductase
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Title:
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2.60 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) h448f/y450l double mutant from staphylococcus aureus in complex with NAD+ and bme-free cys289
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Structure:
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Betaine-aldehyde dehydrogenase. Chain: a, b, c, d, e, f, g, h. Engineered: yes. Mutation: yes
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Source:
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Staphylococcus aureus (strain col). Organism_taxid: 93062. Strain: col. Gene: betb, sacol2628. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Resolution:
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2.60Å
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R-factor:
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0.162
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R-free:
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0.232
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Authors:
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A.S.Halavaty,G.Minasov,C.Chen,J.C.Joo,A.F.Yakunin,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid)
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Key ref:
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A.S.Halavaty
et al.
2.60 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) h448f/y450l double muta staphylococcus aureus in complex with NAD+ and bme-Fr cys289.
To be published,
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Date:
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19-May-15
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Release date:
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27-May-15
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PROCHECK
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Headers
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References
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A0A0M3KL40
(A0A0M3KL40_STAAC) -
Betaine-aldehyde dehydrogenase from Staphylococcus aureus (strain COL)
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Seq:
Struc:
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496 a.a.
499 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.1.2.1.8
- betaine-aldehyde dehydrogenase.
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Reaction:
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betaine aldehyde + NAD+ + H2O = glycine betaine + NADH + 2 H+
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betaine aldehyde
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+
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NAD(+)
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+
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H2O
Bound ligand (Het Group name = )
corresponds exactly
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=
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glycine betaine
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+
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NADH
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+
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2
×
H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
