PDBsum entry 4zv3

Hydrolase

PDB id: 4zv3

Contents

Protein chains

299 a.a.

Ligands

COA ×3

PDB id:

4zv3

Name:

Hydrolase

Title:

Crystal structure of the n- and c-terminal domains of mouse acyl-coa thioesterase 7

Structure:

Cytosolic acyl coenzyme a thioester hydrolase. Chain: a, b, c. Fragment: unp residues 55-369. Synonym: acyl-coa thioesterase 7,brain acyl-coa hydrolase,bach,cte- iia,cte-ii,long chain acyl-coa thioester hydrolase. Engineered: yes

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: acot7, bach. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

3.10Å R-factor: 0.244 R-free: 0.296

Authors:

C.M.D.Swarbrick,J.K.Forwood

Key ref:

C.M.D.Swarbrick and j.k.forwood Crystal structure of the n- And c-Terminal domains of acyl-Coa thioesterase 7. To be published, .

Date:

18-May-15 Release date: 03-Jun-15

Protein chains

Q91V12  (BACH_MOUSE) -  Cytosolic acyl coenzyme A thioester hydrolase from Mus musculus

Seq: 381 a.a.

Struc: 299 a.a.

Enzyme reactions

• Enzyme class: E.C.3.1.2.2 - palmitoyl-CoA hydrolase.
• Reaction: hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H⁺

hexadecanoyl-CoA + H2O = hexadecanoate (Bound ligand (Het Group name = COA) corresponds exactly) + CoA + H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site