PDBsum entry 4zry

Protein fibril

PDB id: 4zry

Contents

Protein chains

110 a.a.

104 a.a.

PDB id:

4zry

Name:

Protein fibril

Title:

Crystal structure of the heterocomplex between coil 2b domains of human intermediate filament proteins keratin 1 (krt1) and keratin 10 (krt10)

Structure:

Keratin, type i cytoskeletal 10. Chain: a. Fragment: coil 2b domain (unp residues 337-456). Synonym: cytokeratin-10, ck-10, keratin-10, k10. Engineered: yes. Keratin, type ii cytoskeletal 1. Chain: b. Fragment: coil 2b domain (unp residues 370-489). Synonym: 67 kda cytokeratin, cytokeratin-1, ck-1, hair alpha protein,

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: krt10, kpp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: krt1, krta.

Resolution:

3.30Å R-factor: 0.273 R-free: 0.277

Authors:

C.G.Bunick,T.A.Steitz

Key ref:

C.G.Bunick and L.M.Milstone (2017). The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease. J Invest Dermatol, 137, 142-150. PubMed id: 27595935 DOI: 10.1016/j.jid.2016.08.018

Date:

12-May-15 Release date: 18-May-16

Protein chain

P13645  (K1C10_HUMAN) -  Keratin, type I cytoskeletal 10 from Homo sapiens

Seq: 584 a.a.

Struc: 110 a.a.

Protein chain

P04264  (K2C1_HUMAN) -  Keratin, type II cytoskeletal 1 from Homo sapiens

Seq: 644 a.a.

Struc: 104 a.a.

DOI no: 10.1016/j.jid.2016.08.018

J Invest Dermatol 137:142-150 (2017)

PubMed id: 27595935

The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease.

C.G.Bunick, L.M.Milstone.

ABSTRACT

No abstract given.