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PDBsum entry 4zrw
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protein ligands metals links
Sugar binding protein PDB id
4zrw

 

 

 

 

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JSmol PyMol  
Contents
Protein chain
146 a.a.
Ligands
GLC-GLC
Metals
_CA ×3
Waters ×56
PDB id:
4zrw
Name: Sugar binding protein
Title: Structure of cow mincle complexed with trehalose
Structure: Mincle protein. Chain: a. Fragment: unp residues 64-208. Engineered: yes
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: clec4e. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.60Å     R-factor:   0.155     R-free:   0.208
Authors: H.Feinberg,N.D.S.Rambaruth,M.E.Taylor,K.Drickamer,W.I.Weis
Key ref: H.Feinberg et al. (2016). Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle. J Biol Chem, 291, 21222-21233. PubMed id: 27542410 DOI: 10.1074/jbc.M116.749515
Date:
12-May-15     Release date:   25-May-16    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
E1BHM0  (E1BHM0_BOVIN) -  C-type lectin domain family 4 member E from Bos taurus
Seq:
Struc: 		211 a.a.
146 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 

 
DOI no: 10.1074/jbc.M116.749515 J Biol Chem 291:21222-21233 (2016)
PubMed id: 27542410  
 
 
Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
H.Feinberg, N.D.Rambaruth, S.A.Jégouzo, K.M.Jacobsen, R.Djurhuus, T.B.Poulsen, W.I.Weis, M.E.Taylor, K.Drickamer.
 
  ABSTRACT  
 
No abstract given.

 

 

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