PDBsum entry 4zre

Hydrolase

PDB id: 4zre

Contents

Protein chain

279 a.a.

Ligands

NAG-NAG-BMA

Metals

_CL

Waters ×193

PDB id:

4zre

Name:

Hydrolase

Title:

Crystal structure of smg1 f278d mutant

Structure:

Lip1, secretory lipase (family 3). Chain: a. Fragment: unp residues 20-304. Engineered: yes. Mutation: yes

Source:

Malassezia globosa. Dandruff-associated fungus. Organism_taxid: 425265. Strain: atcc mya-4612 / cbs 7966. Gene: mgl_0797. Expressed in: komagataella pastoris. Expression_system_taxid: 4922.

Resolution:

2.00Å R-factor: 0.157 R-free: 0.205

Authors:

J.Xu,H.Xu,S.Hou,J.Liu

Key ref:

S.Guo et al. (2015). Structure of product-bound SMG1 lipase: active site gating implications. Febs J, 282, 4538-4547. PubMed id: 26365206 DOI: 10.1111/febs.13513

Date:

12-May-15 Release date: 23-Sep-15

Protein chain

A8PUY1  (A8PUY1_MALGO) -  Secreted mono- and diacylglycerol lipase LIP1 from Malassezia globosa (strain ATCC MYA-4612 / CBS 7966)

Seq: 304 a.a.

Struc: 279 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.1.1.- - ?????

DOI no: 10.1111/febs.13513

Febs J 282:4538-4547 (2015)

PubMed id: 26365206

Structure of product-bound SMG1 lipase: active site gating implications.

S.Guo, J.Xu, I.V.Pavlidis, D.Lan, U.T.Bornscheuer, J.Liu, Y.Wang.

ABSTRACT

No abstract given.