PDBsum entry 4znd

Transferase

PDB id: 4znd

Contents

Protein chain

436 a.a.

Ligands

S3P

PO4 ×2

BME

Metals

__K

Waters ×82

PDB id:

4znd

Name:

Transferase

Title:

2.55 angstrom resolution structure of 3-phosphoshikimate 1- carboxyvinyltransferase (aroa) from coxiella burnetii in complex with shikimate-3-phosphate, phosphate, and potassium

Structure:

3-phosphoshikimate 1-carboxyvinyltransferase. Chain: a. Synonym: 5-enolpyruvylshikimate-3-phosphate synthase,epsps. Engineered: yes

Source:

Coxiella burnetii (strain rsa 493 / nine mile phase i). Organism_taxid: 227377. Strain: rsa 493 / nine mile phase i. Gene: aroa, cbu_0526. Expressed in: escherichia coli. Expression_system_taxid: 511693.

Resolution:

2.55Å R-factor: 0.169 R-free: 0.238

Authors:

S.H.Light,G.Minasov,S.N.Krishna,K.Kwon,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid)

Key ref:

S.H.Light et al. 2.55 angstrom resolution structure of 3-Phosphoshikim 1-Carboxyvinyltransferase (aroa) from coxiella burnet complex with shikimate-3-Phosphate, Phosphate, And po. To be published, .

Date:

04-May-15 Release date: 13-May-15

Protein chain

Q83E11  (AROA_COXBU) -  3-phosphoshikimate 1-carboxyvinyltransferase from Coxiella burnetii (strain RSA 493 / Nine Mile phase I)

Seq: 438 a.a.

Struc: 436 a.a.

Enzyme reactions

• Enzyme class: E.C.2.5.1.19 - 3-phosphoshikimate 1-carboxyvinyltransferase.
• Pathway: Shikimate and Chorismate Biosynthesis
• Reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3- phosphoshikimate + phosphate

3-phosphoshikimate + phosphoenolpyruvate (Bound ligand (Het Group name = S3P) matches with 52.94% similarity) = 5-O-(1-carboxyvinyl)-3- phosphoshikimate + phosphate (Bound ligand (Het Group name = PO4) corresponds exactly)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site