spacer
spacer

PDBsum entry 4zk4

Go to PDB code: 
protein ligands metals Protein-protein interface(s) links
Acetylcholine binding protein PDB id
4zk4

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chains
211 a.a.
Ligands
SO4 ×5
PG4
TII ×2
Metals
_MG ×2
Waters ×439
PDB id:
4zk4
Name: Acetylcholine binding protein
Title: Crystal structure of a chimeric acetylcholine binding protein from aplysia californica (ac-achbp) containing loop c from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy- pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane
Structure: Soluble acetylcholine receptor, neuronal acetylcholine receptor subunit alpha-3 chimera. Chain: a, b, c, d, e. Fragment: unp residues 18-198 + 215-236 from aplysia californica linked by loop c (unp residues 215-230) from homo sapiens. Engineered: yes
Source: Aplysia californica, homo sapiens. California sea hare, human. Organism_taxid: 6500, 9606. Gene: chrna3, nachra3. Expressed in: homo sapiens. Expression_system_taxid: 9606
Resolution:
1.90Å     R-factor:   0.183     R-free:   0.213
Authors: J.Bobango,J.Wu,T.T.Talley
Key ref: J.Bobango et al. Crystal structure of a chimeric acetylcholine binding protein from aplysia californica (ac-Achbp) containin c from the human alpha 3 nicotinic acetylcholine rece complex with 7-(5-Isopropoxy-Pyridin-3-Yl)-1-Methyl-1, 7-Diaza-Spiro[4.4]nonane.. To be published, .
Date:
29-Apr-15     Release date:   13-May-15    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P32297  (ACHA3_HUMAN) -  Neuronal acetylcholine receptor subunit alpha-3 from Homo sapiens
Seq:
Struc:
505 a.a.
211 a.a.*
Protein chains
Pfam   ArchSchema ?
Q8WSF8  (Q8WSF8_APLCA) -  Soluble acetylcholine receptor from Aplysia californica
Seq:
Struc:
236 a.a.
211 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 163 residue positions (black crosses)

 

spacer

spacer