PDBsum entry 4z9q

Hydrolase

PDB id: 4z9q

Contents

Protein chain

224 a.a.

Waters ×62

PDB id:

4z9q

Name:

Hydrolase

Title:

Crystal structure of oxa-58 with disordered active site

Structure:

Beta-lactamase oxa-58. Chain: a. Engineered: yes

Source:

Acinetobacter baumannii acicu. Organism_taxid: 405416. Strain: acicu. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

2.23Å R-factor: 0.195 R-free: 0.253

Authors:

S.Pratap,P.K.Gill,D.Golemi-Kotra,P.Kumar

Key ref:

S.Pratap et al. Crystal structure of oxa-58 with disordered active si. To be published, .

Date:

11-Apr-15 Release date: 13-Apr-16

Protein chain

A0A182DW26  (A0A182DW26_ACIBC) -  Beta-lactamase from Acinetobacter baumannii (strain ACICU)

Seq: 280 a.a.

Struc: 224 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.5.2.6 - beta-lactamase.
• Pathway: Penicillin Biosynthesis and Metabolism
• Reaction: a beta-lactam + H2O = a substituted beta-amino acid
• Cofactor: Zn(2+)