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PDBsum entry 4z7y
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PDB id:
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Lyase
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Title:
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Diphosphomevalonate decarboxylase from the sulfolobus solfataricus, space group p21
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Structure:
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Diphosphomevalonate decarboxylase. Chain: a, b, c, d, e, f. Fragment: unp residues 2-325. Synonym: dmd. Engineered: yes
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Source:
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Sulfolobus solfataricus (strain atcc 35092 / dsm 1617 / jcm 11322 / p2). Organism_taxid: 273057. Strain: atcc 35092 / dsm 1617 / jcm 11322 / p2. Gene: sso2989. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.70Å
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R-factor:
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0.255
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R-free:
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0.277
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Authors:
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A.Hattori,H.Unno,H.Hemmi
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Key ref:
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A.Hattori
et al.
(2015).
In Vivo Formation of the Protein Disulfide Bond That Enhances the Thermostability of Diphosphomevalonate Decarboxylase, an Intracellular Enzyme from the Hyperthermophilic Archaeon Sulfolobus solfataricus.
J Bacteriol,
197,
3463-3471.
PubMed id:
DOI:
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Date:
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08-Apr-15
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Release date:
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16-Sep-15
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PROCHECK
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Headers
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References
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Q97UL5
(DMD_SULSO) -
Diphosphomevalonate decarboxylase from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
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Seq:
Struc:
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325 a.a.
324 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.4.1.1.33
- diphosphomevalonate decarboxylase.
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Pathway:
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Terpenoid biosynthesis
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Reaction:
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(R)-5-diphosphomevalonate + ATP = isopentenyl diphosphate + ADP + phosphate + CO2
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(R)-5-diphosphomevalonate
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+
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ATP
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=
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isopentenyl diphosphate
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+
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ADP
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+
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phosphate
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+
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CO2
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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DOI no:
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J Bacteriol
197:3463-3471
(2015)
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PubMed id:
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In Vivo Formation of the Protein Disulfide Bond That Enhances the Thermostability of Diphosphomevalonate Decarboxylase, an Intracellular Enzyme from the Hyperthermophilic Archaeon Sulfolobus solfataricus.
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A.Hattori,
H.Unno,
S.Goda,
K.Motoyama,
T.Yoshimura,
H.Hemmi.
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ABSTRACT
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