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PDBsum entry 4z33

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protein ligands Protein-protein interface(s) links
Signaling protein PDB id
4z33

 

 

 

 

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Contents
Protein chains
166 a.a.
Ligands
LYS-GLY-GLU-THR-
ALA-VAL
GLU-THR-ALA-VAL
ACT ×4
GOL ×2
IP2
Waters ×163
PDB id:
4z33
Name: Signaling protein
Title: Crystal structure of the syntenin pdz1 and pdz2 tandem in complex with the frizzled 7 c-terminal fragment and pip2
Structure: Syntenin-1. Chain: a, b. Fragment: residues 111-275. Synonym: melanoma differentiation-associated protein 9,mda-9,pro-tgf- alpha cytoplasmic domain-interacting protein 18,tacip18,scaffold protein pbp1,syndecan-binding protein 1. Engineered: yes. Lys-gly-glu-thr-ala-val. Chain: c, d.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: sdcbp, mda9, sycl. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Organism_taxid: 9606
Resolution:
2.45Å     R-factor:   0.184     R-free:   0.239
Authors: A.L.Egea-Jimenez,R.Gallardo,A.Garcia-Pino,Y.Ivarsson,A.M.Wawrzyniak, R.Kashyap,R.Loris,J.Schymkowitz,F.Rousseau,P.Zimmermann
Key ref: A.L.Egea-Jimenez et al. Crystal structure of the syntenin pdz1 and pdz2 tande complex with the frizzled 7 c-Terminal fragment and p. To be published, .
Date:
30-Mar-15     Release date:   29-Jun-16    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
O00560  (SDCB1_HUMAN) -  Syntenin-1 from Homo sapiens
Seq:
Struc:
298 a.a.
166 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 

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