PDBsum entry 4z0r

Protein binding/structural protein

PDB id: 4z0r

Contents

Protein chains

57 a.a.

Ligands

ALA-ARG-THR-M3L-GLN-THR-ALA-ARG-LYS-SER

SO4

UNX ×24

EDO

Metals

_ZN ×3

Waters ×130

PDB id:

4z0r

Name:

Protein binding/structural protein

Title:

Crystal structure of the cw domain of zcwpw2 mutant f78r in complex with histone h3 peptide

Structure:

Zinc finger cw-type pwwp domain protein 2. Chain: a, b, c. Fragment: cw domain (unp residues 21-78). Synonym: zcwpw2. Engineered: yes. Mutation: yes. Histone h3.1. Chain: d. Fragment: n-terminal tail (unp residues 2-16).

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: zcwpw2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606

Resolution:

1.75Å R-factor: 0.178 R-free: 0.192

Authors:

Y.Liu,W.Tempel,C.Bountra,C.H.Arrowsmith,A.M.Edwards,J.Min,Structural Genomics Consortium (Sgc)

Key ref:

Y.Liu et al. Crystal structure of the cw domain of zcwpw2 mutant f complex with histone h3 peptide. To be published, .

Date:

26-Mar-15 Release date: 08-Apr-15

Protein chains

Q504Y3  (ZCPW2_HUMAN) -  Zinc finger CW-type PWWP domain protein 2 from Homo sapiens

Seq: 356 a.a.

Struc: 57 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)