PDBsum entry 4z02

Histone-binding protein

PDB id: 4z02

Contents

Protein chains

119 a.a.

104 a.a.

Ligands

4K8 ×2

EDO

UNX ×10

Waters ×96

PDB id:

4z02

Name:

Histone-binding protein

Title:

Crystal structure of brd1 in complex with isoquinoline-3-carboxylic acid

Structure:

Bromodomain-containing protein 1. Chain: a, b. Fragment: unp residues 925-1049. Synonym: br140-like protein,bromodomain and phd finger-containing protein 2. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: brd1, brl, brpf2. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.87Å R-factor: 0.229 R-free: 0.257

Authors:

A.Dong,A.Iqbal,J.R.Walker,C.Bountra,C.H.Arrowsmith,A.M.Edwards, P.J.Brown,Structural Genomics Consortium (Sgc)

Key ref:

A.Iqbal et al. Crystal structure of brd1 incomplex with isoquinoline-3-Carboxylic acid. To be published, .

Date:

25-Mar-15 Release date: 22-Apr-15

Protein chain

O95696  (BRD1_HUMAN) -  Bromodomain-containing protein 1 from Homo sapiens

Seq: 1058 a.a.

Struc: 119 a.a.

Protein chain

O95696  (BRD1_HUMAN) -  Bromodomain-containing protein 1 from Homo sapiens

Seq: 1058 a.a.

Struc: 104 a.a.