PDBsum entry 4y1v

Sugar binding protein

PDB id: 4y1v

Contents

Protein chains

133 a.a.

Ligands

MAG-GAL ×2

Waters ×60

PDB id:

4y1v

Name:

Sugar binding protein

Title:

Complex of human galectin-1 and galbeta1-3glcnac

Structure:

Galectin-1. Chain: a, b. Synonym: gal-1,14 kda laminin-binding protein,hlbp14,14 kda lectin, beta-galactoside-binding lectin l-14-i,galaptin,hbl,hpl,lactose- binding lectin 1,lectin galactoside-binding soluble 1,putative mapk- activating protein pm12,s-lac lectin 1. Engineered: yes. Other_details: the n-terminus residues are missing due to disorder.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: lgals1. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.32Å R-factor: 0.222 R-free: 0.268

Authors:

H.Y.Lin,T.J.Hsieh,C.H.Lin

Key ref:

H.Y.Lin et al. Structural basis of human galectin-1 inhibition with values in the micro- To nanomolar range. To be published, .

Date:

09-Feb-15 Release date: 06-Apr-16

Protein chains

P09382  (LEG1_HUMAN) -  Galectin-1 from Homo sapiens

Seq: 135 a.a.

Struc: 133 a.a.*

* PDB and UniProt seqs differ at 5 residue positions (black crosses)