PDBsum entry 4xzk

Transferase

PDB id: 4xzk

Contents

Protein chain

215 a.a.

Ligands

AG2

Waters ×105

PDB id:

4xzk

Name:

Transferase

Title:

Crystal structure of adp-ribosyltransferase vis in complex with agmatine

Structure:

Putative NAD(+)--arginine adp-ribosyltransferase vis. Chain: a. Synonym: putative mono(adp-ribosyl)transferase,mart,toxin vis. Engineered: yes

Source:

Vibrio splendidus. Organism_taxid: 29497. Gene: v12b01_18061. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.80Å R-factor: 0.195 R-free: 0.221

Authors:

R.Pfoh,R.Ravulapalli,A.R.Merrill,E.F.Pai

Key ref:

R.Ravulapalli et al. Vis toxin, An ADP-Ribosyltransferase from vibrio sple. To be published, .

Date:

04-Feb-15 Release date: 20-Jan-16

Protein chain

A3UNN4  (VIS_VIBS1) -  Putative NAD(+)--arginine ADP-ribosyltransferase Vis from Vibrio splendidus (strain 12B01)

Seq: 249 a.a.

Struc: 215 a.a.

Enzyme reactions

• Enzyme class: E.C.2.4.2.31 - NAD(+)--protein-arginine ADP-ribosyltransferase.
• Reaction: L-arginyl-[protein] + NAD⁺ = N(omega)-(ADP-D-ribosyl)-L-arginyl- [protein] + nicotinamide + H⁺

L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl- [protein] + nicotinamide + H(+) (Bound ligand (Het Group name = AG2) matches with 50.00% similarity)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site