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PDBsum entry 4xr2
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protein dna_rna ligands metals links
Replication/DNA PDB id
4xr2

 

 

 

 

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Contents
Protein chain
305 a.a.
DNA/RNA
Ligands
MPD
EDO
Metals
IOD ×2
Waters ×69
PDB id:
4xr2
Name: Replication/DNA
Title: Escherichia coli replication terminator protein (tus) h114a mutant complexed with DNA- tera lock.
Structure: DNA replication terminus site-binding protein. Chain: a. Synonym: ter-binding protein. Engineered: yes. Mutation: yes. DNA (5'-d( Tp Ap Gp Tp Tp Ap Cp Ap Ap Cp Ap Tp Ap C)-3'). Chain: b. Engineered: yes. Other_details: tera complimentary strand.
Source: Escherichia coli (strain k12). Organism_taxid: 83333. Strain: k12. Gene: tus, tau, b1610, jw1602. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Escherichia coli. Organism_taxid: 562.
Resolution:
2.35Å     R-factor:   0.222     R-free:   0.266
Authors: A.J.Oakley
Key ref: M.M.Elshenawy et al. (2015). Replisome speed determines the efficiency of the Tus-Ter replication termination barrier. Nature, 525, 394-398. PubMed id: 26322585 DOI: 10.1038/nature14866
Date:
20-Jan-15     Release date:   26-Aug-15    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P16525  (TUS_ECOLI) -  DNA replication terminus site-binding protein from Escherichia coli (strain K12)
Seq:
Struc: 		309 a.a.
305 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

DNA/RNA chains
  T-A-G-T-T-A-C-A-A-C-A-T-A-C 14 bases
  T-G-A-T-A-T-G-T-T-G-T-A-A-C-T-A 16 bases

 

 
DOI no: 10.1038/nature14866 Nature 525:394-398 (2015)
PubMed id: 26322585  
 
 
Replisome speed determines the efficiency of the Tus-Ter replication termination barrier.
M.M.Elshenawy, S.Jergic, Z.Q.Xu, M.A.Sobhy, M.Takahashi, A.J.Oakley, N.E.Dixon, S.M.Hamdan.
 
  ABSTRACT  
 
No abstract given.

 

 

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