PDBsum entry 4xki

Growth factor

PDB id: 4xki

Contents

Protein chains

145 a.a.

Ligands

SO4 ×2

PO4 ×8

GOL

2PE

Waters ×260

PDB id:

4xki

Name:

Growth factor

Title:

Human fibroblast growth factor - 1 (fgf-1) mutant s116r

Structure:

Fibroblast growth factor 1. Chain: a, b. Synonym: fgf-1,acidic fibroblast growth factor,afgf,endothelial cell growth factor,ecgf,heparin-binding growth factor 1,hbgf-1. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: fgf1, fgfa. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.00Å R-factor: 0.178 R-free: 0.215

Authors:

X.Xia

Key ref:

X.Xia Biophysical characterizations of fibroblast growth fa 1 mutant with increased heparin binding affinity. To be published, .

Date:

12-Jan-15 Release date: 20-Jan-16

Protein chains

P05230  (FGF1_HUMAN) -  Fibroblast growth factor 1 from Homo sapiens

Seq: 155 a.a.

Struc: 145 a.a.*

* PDB and UniProt seqs differ at 8 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.?