spacer
spacer

PDBsum entry 4x7d
Go to PDB code: 
protein ligands Protein-protein interface(s) links
Viral protein PDB id
4x7d

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chains
307 a.a.
105 a.a.
121 a.a.
Ligands
EDO ×2
Waters ×419
PDB id:
4x7d
Name: Viral protein
Title: Crystal structure of 2012 nsw gii.4 p domain in complex with nano-85
Structure: Vp1. Chain: a, b. Fragment: unp residues 225-530. Engineered: yes. Nano-85 nanobody. Chain: c, d. Fragment: vhh. Engineered: yes
Source: Norovirus hu/gii.4/sydney/nsw0514/2012/au. Organism_taxid: 1241973. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Lama glama. Llama. Organism_taxid: 9844. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.15Å     R-factor:   0.198     R-free:   0.238
Authors: A.D.Koromyslova,G.S.Hansman
Key ref: A.D.Koromyslova and G.S.Hansman (2015). Nanobody binding to a conserved epitope promotes norovirus particle disassembly. J Virol, 89, 2718-2730. PubMed id: 25520510 DOI: 10.1128/JVI.03176-14
Date:
09-Dec-14     Release date:   31-Dec-14    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
K4LM89  (K4LM89_9CALI) -  VP1 from Norovirus Hu/GII.4/Sydney/NSW0514/2012/AU
Seq:
Struc: 		 
Seq:
Struc: 		540 a.a.
307 a.a.*
Protein chain
No UniProt id for this chain
Struc: 105 a.a.
Protein chain
No UniProt id for this chain
Struc: 121 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 

 
DOI no: 10.1128/JVI.03176-14 J Virol 89:2718-2730 (2015)
PubMed id: 25520510  
 
 
Nanobody binding to a conserved epitope promotes norovirus particle disassembly.
A.D.Koromyslova, G.S.Hansman.
 
  ABSTRACT  
 
No abstract given.

 

 

spacer
spacer