PDBsum entry 4x7c

Viral protein

PDB id: 4x7c

Contents

Protein chains

307 a.a.

116 a.a.

120 a.a.

Waters ×428

PDB id:

4x7c

Name:

Viral protein

Title:

Crystal structure of saga-2006 gii.4 p domain in complex with nano-85

Structure:

Vp1. Chain: a, b. Fragment: unp residues 225-530. Engineered: yes. Nano-85 nanobody. Chain: c, d. Fragment: vhh. Engineered: yes

Source:

Norovirus hu/gii-4/saga1/2006/jp. Organism_taxid: 546980. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Vicugna pacos. Organism_taxid: 30538. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.00Å R-factor: 0.169 R-free: 0.218

Authors:

A.D.Koromyslova,G.S.Hansman

Key ref:

A.D.Koromyslova and G.S.Hansman (2015). Nanobody binding to a conserved epitope promotes norovirus particle disassembly. J Virol, 89, 2718-2730. PubMed id: 25520510 DOI: 10.1128/JVI.03176-14

Date:

09-Dec-14 Release date: 31-Dec-14

Protein chains

B5BTR4  (B5BTR4_9CALI) -  VP1 from Norovirus Hu/GII-4/Saga1/2006/JP

Seq: 540 a.a.

Struc: 307 a.a.*

Protein chain

No UniProt id for this chain

Struc: 116 a.a.

Protein chain

No UniProt id for this chain

Struc: 120 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)

DOI no: 10.1128/JVI.03176-14

J Virol 89:2718-2730 (2015)

PubMed id: 25520510

Nanobody binding to a conserved epitope promotes norovirus particle disassembly.

A.D.Koromyslova, G.S.Hansman.

ABSTRACT

No abstract given.