PDBsum entry 4x1g

Gene regulation

PDB id: 4x1g

Contents

Protein chain

279 a.a.

Ligands

3WF

3WG

MPD

IPA

Waters ×122

PDB id:

4x1g

Name:

Gene regulation

Title:

Crystal structure of the hpxr-lbd in complex with the synthetic estrogen 17alpha-ethinylestradiol and the pesticide trans-nonachlor

Structure:

Nuclear receptor subfamily 1 group i member 2. Chain: a. Fragment: unp residues 130-434. Synonym: orphan nuclear receptor par1,orphan nuclear receptor pxr, pregnane x receptor,steroid and xenobiotic receptor,sxr. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: nr1i2, pxr. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

2.25Å R-factor: 0.176 R-free: 0.218

Authors:

V.Delfosse,T.Huet,W.Bourguet

Date:

24-Nov-14 Release date: 09-Sep-15

Protein chain

O75469  (NR1I2_HUMAN) -  Nuclear receptor subfamily 1 group I member 2 from Homo sapiens

Seq: 434 a.a.

Struc: 279 a.a.