PDBsum entry 4w2h

RIBOSOME/ANTIBIOTIC

PDB id

4w2h

Contents

			Protein chains

					×98 chains

			DNA/RNA

					× DNA chains ×12 RNA chains

			Ligands

					PCY ×2


					SF4 ×2


					K ×2

			Metals

					_ZN ×12


					_MG ×2043

			Waters ×2763

PDB id:

4w2h

Links

Name:

RIBOSOME/ANTIBIOTIC

Title:

Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P sit

Structure:

PROTEIN/RNA Complex

Authors:

Polikanov, Y.S., Osterman, I.A., Szal, T., Tashlitsky, V.N., Serebryakova, M.V., Kusochek, P., Bulkley, D., Malanicheva, I.A., Efimenko, T.A., Efremenkova, O.V., Konevega, A.L., Shaw, K.J., Bogdanov, A.A., Rodnina, M.V., Dontsova, O.A., Mankin, A.S., Steitz, T.A., Sergiev, P.V.

Key ref:

(2014). Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.. Mol.Cell, 56, 531-540. PubMed id: 25306919

Note. PDBsum analyses are not available for this structure because of its large size. To get more detailed information on it, please go to its PDBe page.