PDBsum entry 4pcw

Metal binding protein

PDB id: 4pcw

Contents

Protein chains

87 a.a.

Ligands

2PE ×2

Metals

_CA ×8

Waters ×120

PDB id:

4pcw

Name:

Metal binding protein

Title:

Crystal structure of the n-terminal domain of human profilaggrin at 2.2 a resolution

Structure:

Filaggrin. Chain: a, b, c, d. Fragment: n-terminal domain (unp residues 1-92). Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: flg. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.20Å R-factor: 0.198 R-free: 0.242

Authors:

C.G.Bunick,T.A.Steitz

Key ref:

C.G.Bunick et al. (2015). Crystal Structure of Human Profilaggrin S100 Domain and Identification of Target Proteins Annexin II, Stratifin, and HSP27. J Invest Dermatol, 135, 1801-1809. PubMed id: 25760235 DOI: 10.1038/jid.2015.102

Date:

16-Apr-14 Release date: 01-Apr-15

Protein chains

P20930  (FILA_HUMAN) -  Filaggrin from Homo sapiens

Seq: 4061 a.a.

Struc: 87 a.a.

DOI no: 10.1038/jid.2015.102

J Invest Dermatol 135:1801-1809 (2015)

PubMed id: 25760235

Crystal Structure of Human Profilaggrin S100 Domain and Identification of Target Proteins Annexin II, Stratifin, and HSP27.

C.G.Bunick, R.B.Presland, O.T.Lawrence, D.J.Pearton, L.M.Milstone, T.A.Steitz.

ABSTRACT

No abstract given.