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PDBsum entry 4mhq
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PDB id:
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Replication
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Title:
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Crystal structure of human primase catalytic subunit
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Structure:
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DNA primase small subunit. Chain: a. Fragment: full length. Synonym: DNA primase 49 kda subunit, p49. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: prim1. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.20Å
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R-factor:
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0.179
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R-free:
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0.233
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Authors:
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K.R.Park,J.Y.An,Y.Lee,H.S.Youn,J.G.Lee,J.Y.Kang,T.G.Kim,J.J.Lim, S.H.Eom,J.Wang
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Key ref:
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K.R.Park
et al.
Crystal structure of human primase catalytic subunit.
To be published,
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Date:
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30-Aug-13
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Release date:
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03-Sep-14
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PROCHECK
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Headers
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References
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P49642
(PRI1_HUMAN) -
DNA primase small subunit from Homo sapiens
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Seq:
Struc:
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420 a.a.
400 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.7.102
- Dna primase aep.
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Reaction:
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1.
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ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate
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2.
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ssDNA + n dNTP = ssDNA/pppdN(pdN)n-1 hybrid + (n-1) diphosphate
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ssDNA
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+
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n
NTP
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=
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ssDNA/pppN(pN)n-1 hybrid
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+
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(n-1) diphosphate
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ssDNA
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+
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n
dNTP
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=
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ssDNA/pppdN(pdN)n-1 hybrid
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+
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(n-1) diphosphate
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
