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PDBsum entry 4mgc
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Hormone receptor
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PDB id
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4mgc
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PDB id:
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| Name: |
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Hormone receptor
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Title:
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Crystal structure of hera-lbd (y537s) in complex with benzophenone-2
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Structure:
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Estrogen receptor. Chain: a, b. Fragment: ligand binding domain (unp residues 302-552). Synonym: er, er-alpha, estradiol receptor, nuclear receptor subfamily 3 group a member 1. Engineered: yes. Mutation: yes. Nuclear receptor coactivator 1. Chain: f, g.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: esr, esr1, nr3a1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
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Resolution:
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2.15Å
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R-factor:
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0.186
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R-free:
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0.241
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Authors:
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V.Delfosse,M.Grimaldi,W.Bourguet
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Key ref:
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V.Delfosse
et al.
(2014).
Structural and functional profiling of environmental ligands for estrogen receptors.
Environ Health Perspect,
122,
1306-1313.
PubMed id:
DOI:
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Date:
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28-Aug-13
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Release date:
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03-Sep-14
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PROCHECK
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Headers
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References
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P03372
(ESR1_HUMAN) -
Estrogen receptor from Homo sapiens
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Seq:
Struc:
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595 a.a.
238 a.a.*
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Key: |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 4 residue positions (black
crosses)
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DOI no:
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Environ Health Perspect
122:1306-1313
(2014)
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PubMed id:
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Structural and functional profiling of environmental ligands for estrogen receptors.
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V.Delfosse,
M.Grimaldi,
V.Cavaillès,
P.Balaguer,
W.Bourguet.
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ABSTRACT
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Links
