PDBsum entry 4m7l

Blood clotting/immune system

PDB id: 4m7l

Contents

Protein chains

194 a.a.

220 a.a.

223 a.a.

PDB id:

4m7l

Name:

Blood clotting/immune system

Title:

Crystal structure of the complex between human tissue factor extracellular domain and antibody 10h10 fab fragment

Structure:

Tissue factor. Chain: t. Fragment: extracellular domain (unp residues 37-245). Synonym: tf, coagulation factor iii, thromboplastin. Engineered: yes. 10h10 light chain. Chain: l. Fragment: see remark 999. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: f3. Expressed in: escherichia coli. Expression_system_taxid: 562. Mus musculus, homo sapiens. Mouse, human. Organism_taxid: 10090, 9606.

Resolution:

3.40Å R-factor: 0.245 R-free: 0.289

Authors:

A.Teplyakov,G.Obmolova,T.Malia,G.L.Gilliland

Key ref:

A.Teplyakov et al. Crystal structure of the complex between human tissue extracellular domain and antibody 10h10 FAB fragment. To be published, .

Date:

12-Aug-13 Release date: 13-Aug-14

Protein chain

P13726  (TF_HUMAN) -  Tissue factor from Homo sapiens

Seq: 295 a.a.

Struc: 194 a.a.

Protein chain

No UniProt id for this chain

Struc: 220 a.a.

Protein chain

No UniProt id for this chain

Struc: 223 a.a.