PDBsum entry 4m4c

Toxin

PDB id: 4m4c

Contents

Protein chains

65 a.a.

Ligands

SO4 ×6

Waters ×100

PDB id:

4m4c

Name:

Toxin

Title:

Crystal structure of rhodostomin argdp mutant

Structure:

Zinc metalloproteinase/disintegrin. Chain: a, b, c, d. Fragment: unp residues 408-475. Synonym: snake venom metalloproteinase rhodostoxin, svmp, hemorrhagic protein, disintegrin rhodostomin, rho, disintegrin kistrin, platelet aggregation activation inhibitor. Engineered: yes. Mutation: yes

Source:

Calloselasma rhodostoma. Malayan pit viper. Organism_taxid: 8717. Gene: rhod. Expressed in: pichia pastoris. Expression_system_taxid: 4922.

Resolution:

1.80Å R-factor: 0.181 R-free: 0.238

Authors:

Y.T.Chang,W.Y.Jeng,J.H.Shiu,C.Y.Chen,W.J.Chuang

Key ref:

Y.T.Chang et al. Effect of c-Terminal proline residue adjacent to the motif in rhodostomin on its activity and structure. To be published, .

Date:

07-Aug-13 Release date: 13-Aug-14

Protein chains

P30403  (VM2RH_CALRH) -  Zinc metalloproteinase/disintegrin from Calloselasma rhodostoma

Seq: 478 a.a.

Struc: 65 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.4.24.- - ?????