PDBsum entry 4k6c

Oxidoreductase

PDB id: 4k6c

Contents

Protein chains

245 a.a.

Ligands

EDO ×2

Metals

_CL

Waters ×393

PDB id:

4k6c

Name:

Oxidoreductase

Title:

X-ray crystal structure of a putative acetoacyl-coa reductase from burkholderia cenocepacia

Structure:

Acetoacetyl-coa reductase. Chain: a, b. Engineered: yes

Source:

Burkholderia cenocepacia. Organism_taxid: 216591. Strain: j2315. Gene: phbb, bcej2315_08230, bcal0833. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.85Å R-factor: 0.162 R-free: 0.196

Authors:

Seattle Structural Genomics Center For Infectious Disease (Ssgcid)

Key ref:

J.W.Fairman et al. X-Ray crystal structure of a putative acetoacyl-Coa reductase from burkholderia cenocepacia. To be published, .

Date:

15-Apr-13 Release date: 22-May-13

Protein chains

B4EAU4  (B4EAU4_BURCJ) -  Acetoacetyl-CoA reductase from Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)

Seq: 247 a.a.

Struc: 245 a.a.

Enzyme reactions

• Enzyme class: E.C.1.1.1.36 - acetoacetyl-CoA reductase.
• Reaction: a (3R)-3-hydroxyacyl-CoA + NADP⁺ = a 3-oxoacyl-CoA + NADPH + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site