 |
PDBsum entry 4jyx
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Transferase
|
|
|
Title:
|
|
Crystal structure of polyprenyl synthase patl_3739 (target efi-509195) from pseudoalteromonas atlantica, complex with inorganic phosphate and an unknown ligand
|
|
Structure:
|
|
Trans-hexaprenyltranstransferase. Chain: a, b, c, d, e, f, g, h. Engineered: yes
|
|
Source:
|
|
Pseudoalteromonas atlantica. Organism_taxid: 342610. Strain: t6c / atcc baa-1087. Gene: patl_3739. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
Resolution:
|
|
|
2.30Å
|
R-factor:
|
0.179
|
R-free:
|
0.239
|
|
|
Authors:
|
|
Y.Patskovsky,R.Toro,R.Bhosle,B.Hillerich,R.D.Seidel,E.Washington, A.Scott Glenn,S.Chowdhury,B.Evans,J.Hammonds,W.D.Zencheck,H.J.Imker, N.Al Obaidi,M.Stead,J.Love,C.D.Poulter,J.A.Gerlt,S.C.Almo,Enzyme Function Initiative (Efi)
|
|
Key ref:
|
|
Y.Patskovsky
et al.
Crystal structure of isoprenoid synthase patl_3739 fr pseudoalteromonas atlantica.
To be published,
.
|
|
|
Date:
|
|
|
01-Apr-13
|
Release date:
|
10-Apr-13
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
|
|
|
|
|
Enzyme class:
|
|
E.C.2.5.1.30
- heptaprenyl diphosphate synthase.
|
|
|
|
|
|
|
Pathway:
|
|
Terpenoid biosynthesis
|
|
|
|
|
|
Reaction:
|
|
4 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = all-trans- heptaprenyl diphosphate + 4 diphosphate
|
|
|
|
|
|
4
×
isopentenyl diphosphate
|
+
|
(2E,6E)-farnesyl diphosphate
|
=
|
all-trans- heptaprenyl diphosphate
|
+
|
4
×
diphosphate
Bound ligand (Het Group name = )
matches with 55.56% similarity
|
|
|
|
|
|
|
|
|
|
|
|
|
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
|
|
|
|
Links
