PDBsum entry 4jxp

Hydrolase

PDB id: 4jxp

Contents

Protein chain

603 a.a.

Ligands

GOL ×4

NAG ×2

NAG-NAG-BMA-BMA

Waters ×114

Obsolete entry

PDB id:

4jxp

Name:

Hydrolase

Title:

Crystal structure of human alpha-l-iduronidase, monoclinic form

Structure:

Alpha-l-iduronidase. Chain: a. Fragment: unp residues 27-653. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: idua. Expressed in: arabidopsis thaliana. Expression_system_taxid: 3702.

Resolution:

2.17Å R-factor: 0.204 R-free: 0.240

Authors:

H.Bie,J.Yin,X.He,A.R.Kermode,M.N.G.James

Key ref:

H.Bie et al. Crystal structure analysis of human alpha-L-Iduronida two crystal forms. To be published, .

Date:

28-Mar-13 Release date: 17-Apr-13

Protein chain

P35475  (IDUA_HUMAN) -  Alpha-L-iduronidase from Homo sapiens

Seq: 653 a.a.

Struc: 603 a.a.

Enzyme reactions

• Enzyme class: E.C.3.2.1.76 - L-iduronidase.
• Reaction: Hydrolysis of alpha-L-iduronosidic linkages in desulfated dermatan.