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PDBsum entry 4jrm

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protein ligands Protein-protein interface(s) links
Transferase PDB id
4jrm

 

 

 

 

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JSmol PyMol  
Contents
Protein chains
412 a.a.
Ligands
ACT ×2
GOL ×2
Waters ×684
PDB id:
4jrm
Name: Transferase
Title: Crystal structure of beta-ketoacyl-acp synthase ii (fabf) from vibrio cholerae (space group p212121) at 1.75 angstrom
Structure: 3-oxoacyl-[acyl-carrier-protein] synthase 2. Chain: d, a, b, c. Synonym: fabf, 3-oxoacyl-[acyl-carrier-protein] synthase ii, beta- ketoacyl-acp synthase ii, kas ii. Engineered: yes
Source: Vibrio cholerae o1. Organism_taxid: 243277. Strain: atcc 39315 / el tor inaba n16961. Gene: fabf, vc2019, vc_2019. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.75Å     R-factor:   0.203     R-free:   0.231
Authors: J.Hou,M.Chruszcz,I.G.Shabalin,H.Zheng,D.R.Cooper,W.F.Anderson, W.Minor,Center For Structural Genomics Of Infectious Diseases (Csgid)
Key ref: J.Hou et al. Crystal structure of beta-Ketoacyl-Acp synthase ii (f from vibrio cholerae (space group p43) at 2.2 angstro. To be published, .
Date:
21-Mar-13     Release date:   03-Apr-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9KQH9  (FABF_VIBCH) -  3-oxoacyl-[acyl-carrier-protein] synthase 2 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Seq:
Struc:
414 a.a.
412 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.3.1.179  - beta-ketoacyl-[acyl-carrier-protein] synthase Ii.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: (9Z)-hexadecenoyl-[ACP] + malonyl-[ACP] + H+ = 3-oxo-(11Z)- octadecenoyl-[ACP] + holo-[ACP] + CO2
(9Z)-hexadecenoyl-[ACP]
+ malonyl-[ACP]
+ H(+)
= 3-oxo-(11Z)- octadecenoyl-[ACP]
+ holo-[ACP]
Bound ligand (Het Group name = ACT)
matches with 75.00% similarity
+ CO2
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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