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PDBsum entry 4jd9

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protein ligands Protein-protein interface(s) links
Protein binding PDB id
4jd9

 

 

 

 

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Contents
Protein chains
(+ 1 more) 118 a.a.
Ligands
SO4 ×43
Waters ×286
PDB id:
4jd9
Name: Protein binding
Title: Contact pathway inhibitor from a sand fly
Structure: 14.5 kda salivary protein. Chain: a, b, c, d, f, e, g. Synonym: pdsp15b. Engineered: yes
Source: Phlebotomus duboscqi. Sandfly. Organism_taxid: 37738. Gene: k03, m03. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
2.60Å     R-factor:   0.199     R-free:   0.237
Authors: J.F.Andersen,X.Xu,P.Alvarenga
Key ref: P.H.Alvarenga et al. (2013). Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate. Arterioscler Thromb Vasc Biol, 33, 2759-2770. PubMed id: 24092749 DOI: 10.1161/ATVBAHA.113.302482
Date:
24-Feb-13     Release date:   16-Oct-13    
PROCHECK
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 Headers
 References

Protein chains
Q06K46  (SP15B_PHLDU) -  Salivary protein 15b from Phlebotomus duboscqi
Seq:
Struc:
142 a.a.
118 a.a.
Key:    Secondary structure  CATH domain

 

 
DOI no: 10.1161/ATVBAHA.113.302482 Arterioscler Thromb Vasc Biol 33:2759-2770 (2013)
PubMed id: 24092749  
 
 
Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate.
P.H.Alvarenga, X.Xu, F.Oliveira, A.C.Chagas, C.R.Nascimento, I.M.Francischetti, M.A.Juliano, L.Juliano, J.Scharfstein, J.G.Valenzuela, J.M.Ribeiro, J.F.Andersen.
 
  ABSTRACT  
 
No abstract given.

 

 

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