 |
PDBsum entry 4jcs
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Lyase
|
|
|
Title:
|
|
Crystal structure of enoyl-coa hydratase/isomerase from cupriavidus metallidurans ch34
|
|
Structure:
|
|
Enoyl-coa hydratase/isomerase. Chain: a. Engineered: yes
|
|
Source:
|
|
Cupriavidus metallidurans. Organism_taxid: 266264. Strain: ch34 / atcc 43123 / dsm 2839. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
Resolution:
|
|
|
1.77Å
|
R-factor:
|
0.211
|
R-free:
|
0.234
|
|
|
Authors:
|
|
S.Eswaramoorthy,S.Chamala,B.Chamala,F.Foti,A.Gizzi,B.Hillerich,A.Kar, J.Lafleur,R.Seidel,G.Villigas,W.Zencheck,N.Al Obaidi,S.C.Almo, S.Swaminathan,New York Structural Genomics Research Consortium (Nysgrc)
|
|
Key ref:
|
|
S.Eswaramoorthy
et al.
Crystal structure of enoyl-Coa hydratase/isomerase fr cupriavidus metallidurans ch34.
To be published,
.
|
|
|
Date:
|
|
|
22-Feb-13
|
Release date:
|
13-Mar-13
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
Q1LBW6
(Q1LBW6_CUPMC) -
Enoyl-CoA hydratase/isomerase from Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)
|
|
|
|
Seq:
Struc:
|
|
|
|
264 a.a.
265 a.a.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
|
|
|
|
|
|
|
|
|
|
|
Enzyme class:
|
|
E.C.4.2.1.17
- enoyl-CoA hydratase.
|
|
|
|
|
|
|
Reaction:
|
|
|
1.
|
a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O
|
|
2.
|
a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O
|
|
|
|
|
|
|
4-saturated-(3S)-3-hydroxyacyl-CoA
|
=
|
(3E)-enoyl-CoA
|
+
|
H2O
|
|
|
|
|
|
|
(3S)-3-hydroxyacyl-CoA
|
=
|
(2E)-enoyl-CoA
|
+
|
H2O
|
|
|
|
|
|
|
|
|
|
|
|
|
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
|
|
|
|
Links
