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PDBsum entry 4hqw
Go to PDB code:
Transferase inhibitor
PDB id
4hqw
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Contents
Protein chain
230 a.a.
Ligands
19O
Metals
_CA
_CL
×4
Waters
×174
Superseded by:
5oeh
PDB id:
4hqw
Links
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CATH
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ProSAT
Name:
Transferase inhibitor
Title:
Molecular tweezers modulate 14-3-3 protein-protein interactions
Structure:
14-3-3 protein sigma. Chain: a. Synonym: epithelial cell marker protein 1, stratifin. Engineered: yes
Source:
Homo sapiens. Human. Organism_taxid: 9606. Gene: hme1, nm_006142, sfn. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.35Å
R-factor:
0.184
R-free:
0.244
Authors:
D.Bier,C.Ottmann
Key ref:
D.Bier et al. (2013). Molecular tweezers modulate 14-3-3 protein-protein interactions.
Nat Chem
,
5
, 234-239.
PubMed id:
23422566
DOI:
10.1038/nchem.1570
Date:
26-Oct-12
Release date:
27-Feb-13
PROCHECK
Headers
References
Protein chain
?
P31947
(1433S_HUMAN) - 14-3-3 protein sigma from Homo sapiens
Seq:
Struc:
248 a.a.
230 a.a.
Key:
PfamA domain
Secondary structure
CATH domain
DOI no:
10.1038/nchem.1570
Nat Chem
5
:234-239 (2013)
PubMed id:
23422566
Molecular tweezers modulate 14-3-3 protein-protein interactions.
D.Bier,
R.Rose,
K.Bravo-Rodriguez,
M.Bartel,
J.M.Ramirez-Anguita,
S.Dutt,
C.Wilch,
F.G.Klärner,
E.Sanchez-Garcia,
T.Schrader,
C.Ottmann.
ABSTRACT
No abstract given.
Links
