PDBsum entry 4f8h

Transport protein

PDB id: 4f8h

Contents

Protein chains

311 a.a.

Ligands

RKE ×5

LMD ×6

PC1 ×10

Waters ×58

PDB id:

4f8h

Name:

Transport protein

Title:

X-ray structure of the anesthetic ketamine bound to the glic pentameric ligand-gated ion channel

Structure:

Proton-gated ion channel. Chain: a, b, c, d, e. Fragment: unp residues 43-359. Synonym: glic, ligand-gated ion channel, lgic. Engineered: yes

Source:

Gloeobacter violaceus. Organism_taxid: 251221. Strain: pcc 7421. Gene: glvi, glr4197. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.99Å R-factor: 0.189 R-free: 0.219

Authors:

J.J.Pan,Q.Chen,D.Willenbring,X.P.Kong,A.Cohen,Y.Xu,P.Tang

Key ref:

J.Pan et al. (2012). Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine. Structure, 20, 1463-1469. PubMed id: 22958642

Date:

17-May-12 Release date: 29-Aug-12

Protein chains

Q7NDN8  (GLIC_GLOVI) -  Proton-gated ion channel from Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)

Seq: 359 a.a.

Struc: 311 a.a.

Enzyme reactions

• Enzyme class: E.C.?

Structure 20:1463-1469 (2012)

PubMed id: 22958642

Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine.

J.Pan, Q.Chen, D.Willenbring, D.Mowrey, X.P.Kong, A.Cohen, C.B.Divito, Y.Xu, P.Tang.

ABSTRACT

No abstract given.