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PDBsum entry 4ezd

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protein ligands Protein-protein interface(s) links
Transport protein PDB id
4ezd

 

 

 

 

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Contents
Protein chains
345 a.a.
Ligands
SEY ×6
BGC ×8
BOG ×10
SPL ×3
Waters ×184
PDB id:
4ezd
Name: Transport protein
Title: Crystal structure of the ut-b urea transporter from bos taurus bound to selenourea
Structure: Urea transporter 1. Chain: a, b, c. Synonym: solute carrier family 14 member 1, urea transporter b, ut-b, urea transporter, erythrocyte. Engineered: yes
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: slc14a1, ut-b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Resolution:
2.50Å     R-factor:   0.199     R-free:   0.229
Authors: Y.Cao,E.J.Levin,M.Zhou,New York Consortium On Membrane Protein Structure (Nycomps)
Key ref: E.J.Levin et al. (2012). Structure and permeation mechanism of a mammalian urea transporter. Proc Natl Acad Sci U S A, 109, 11194-11199. PubMed id: 22733730
Date:
02-May-12     Release date:   27-Jun-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q5QF96  (UT1_BOVIN) -  Urea transporter 1 from Bos taurus
Seq:
Struc:
384 a.a.
345 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
Proc Natl Acad Sci U S A 109:11194-11199 (2012)
PubMed id: 22733730  
 
 
Structure and permeation mechanism of a mammalian urea transporter.
E.J.Levin, Y.Cao, G.Enkavi, M.Quick, Y.Pan, E.Tajkhorshid, M.Zhou.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23222544 D.Strugatsky, R.McNulty, K.Munson, C.K.Chen, S.M.Soltis, G.Sachs, and H.Luecke (2013).
Structure of the proton-gated urea channel from the gastric pathogen Helicobacter pylori.
  Nature, 493, 255-258.
PDB code: 3ux4
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.

 

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