PDBsum entry 4eqh

Hydrolase

PDB id: 4eqh

Contents

Protein chain

114 a.a.

Ligands

WSA

EPE

Waters ×293

PDB id:

4eqh

Name:

Hydrolase

Title:

Crystal structure of histidine triad nucleotide-binding protein 1 (hint1) from human complexed with trp-ams

Structure:

Histidine triad nucleotide-binding protein 1. Chain: a, b. Synonym: hint1, adenosine 5'-monophosphoramidase. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hint1, hint. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.67Å R-factor: 0.145 R-free: 0.173

Authors:

J.Wang,P.Fang,M.Guo

Key ref:

J.Wang et al. (2012). Side chain independent recognition of aminoacyl adenylates by the Hint1 transcription suppressor. J Phys Chem B, 116, 6798-6805. PubMed id: 22329685

Date:

18-Apr-12 Release date: 02-May-12

Protein chains

P49773  (HINT1_HUMAN) -  Adenosine 5'-monophosphoramidase HINT1 from Homo sapiens

Seq: 126 a.a.

Struc: 114 a.a.

Enzyme reactions

• Enzyme class 2: E.C.3.4.22.- - ?????
• Enzyme class 3: E.C.3.9.1.- - ?????

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

J Phys Chem B 116:6798-6805 (2012)

PubMed id: 22329685

Side chain independent recognition of aminoacyl adenylates by the Hint1 transcription suppressor.

J.Wang, P.Fang, P.Schimmel, M.Guo.

ABSTRACT

No abstract given.