PDBsum entry 4elm

Immune system

PDB id: 4elm

Contents

Protein chains

266 a.a.

98 a.a.

179 a.a.

224 a.a.

211 a.a.

Ligands

NAG-NAG

NAG-NAG-BMA-FUC

NAG ×4

SGF ×2

PLM ×2

PDB id:

4elm

Name:

Immune system

Title:

Crystal structure of the mouse cd1d-lysosulfatide-hy19.3 tcr complex

Structure:

Antigen-presenting glycoprotein cd1d1. Chain: a, c. Engineered: yes. Beta-2 microglobulin. Chain: b, d. Synonym: uncharacterized protein. Engineered: yes. Hy19.3 tcr alpha chain (mouse variable domain, human constant domain).

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: cd1.1, cd1d, cd1d1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: b2m, beta-2-microglobulin, mcg_11606, rp23-34e24.5-001. Gene: valpha1 (mouse variable domain, human constant domain. Expressed in: escherichia coli.

Resolution:

3.48Å R-factor: 0.212 R-free: 0.265

Authors:

E.Girardi,I.Maricic,J.Wang,T.T.Mac,P.Iyer,V.Kumar,D.M.Zajonc

Key ref:

E.Girardi et al. (2012). Type II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigens. Nat Immunol, 13, 851-856. PubMed id: 22820602

Date:

11-Apr-12 Release date: 25-Jul-12

Protein chains

P11609  (CD1D1_MOUSE) -  Antigen-presenting glycoprotein CD1d1 from Mus musculus

Seq: 336 a.a.

Struc: 266 a.a.

Protein chains

P01887  (B2MG_MOUSE) -  Beta-2-microglobulin from Mus musculus

Seq: 119 a.a.

Struc: 98 a.a.

Protein chains

No UniProt id for this chain

Struc: 179 a.a.

Protein chain

No UniProt id for this chain

Struc: 224 a.a.

Protein chain

No UniProt id for this chain

Struc: 211 a.a.

Nat Immunol 13:851-856 (2012)

PubMed id: 22820602

Type II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigens.

E.Girardi, I.Maricic, J.Wang, T.T.Mac, P.Iyer, V.Kumar, D.M.Zajonc.

ABSTRACT

No abstract given.