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PDBsum entry 4e8c

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protein ligands Protein-protein interface(s) links
Hydrolase PDB id
4e8c

 

 

 

 

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Contents
Protein chains
594 a.a.
Ligands
GAL ×2
GOL ×15
Waters ×592
PDB id:
4e8c
Name: Hydrolase
Title: Crystal structure of streptococcal beta-galactosidase in complex with galactose
Structure: Glycosyl hydrolase, family 35. Chain: a, b. Synonym: beta-galactosidase. Engineered: yes
Source: Streptococcus pneumoniae. Organism_taxid: 170187. Strain: tigr4. Gene: sp_0060. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.95Å     R-factor:   0.207     R-free:   0.243
Authors: W.Cheng,L.Wang,X.H.Bai,Y.L.Jiang,Q.Li,G.Yu,C.Z.Zhou,Y.X.Chen
Key ref: W.Cheng et al. (2012). Structural insights into the substrate specificity of Streptococcus pneumoniae β(1,3)-galactosidase BgaC. J Biol Chem, 287, 22910-22918. PubMed id: 22593580
Date:
20-Mar-12     Release date:   30-May-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
A0A0H2UN19  (A0A0H2UN19_STRPN) -  Glycosyl hydrolase, family 35 from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Seq:
Struc:
 
Seq:
Struc:
595 a.a.
594 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.2.1.23  - beta-galactosidase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.

 

 
J Biol Chem 287:22910-22918 (2012)
PubMed id: 22593580  
 
 
Structural insights into the substrate specificity of Streptococcus pneumoniae β(1,3)-galactosidase BgaC.
W.Cheng, L.Wang, Y.L.Jiang, X.H.Bai, J.Chu, Q.Li, G.Yu, Q.L.Liang, C.Z.Zhou, Y.Chen.
 
  ABSTRACT  
 
No abstract given.

 

 

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