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PDBsum entry 4dfh

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protein Protein-protein interface(s) links
Cell adhesion PDB id
4dfh

 

 

 

 

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Contents
Protein chains
125 a.a.
Waters ×300
PDB id:
4dfh
Name: Cell adhesion
Title: Crystal structure of cell adhesion molecule nectin-2/cd112 variable domain
Structure: Poliovirus receptor-related protein 2. Chain: a, b. Fragment: ig-like v-type domain, unp residues 32-158. Synonym: herpes virus entry mediator b, herpesvirus entry mediator b, hveb, nectin-2. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hveb, prr2, pvrl2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.85Å     R-factor:   0.172     R-free:   0.194
Authors: J.Liu,X.Qian,Z.Chen,X.Xu,F.Gao,S.Zhang,R.Zhang,J.Qi,G.F.Gao,J.Yan
Key ref: J.Liu et al. (2012). Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226. J Immunol, 188, 5511-5520. PubMed id: 22547693
Date:
23-Jan-12     Release date:   06-Jun-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q92692  (NECT2_HUMAN) -  Nectin-2 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
538 a.a.
125 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

 
J Immunol 188:5511-5520 (2012)
PubMed id: 22547693  
 
 
Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226.
J.Liu, X.Qian, Z.Chen, X.Xu, F.Gao, S.Zhang, R.Zhang, J.Qi, G.F.Gao, J.Yan.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23202587 X.Zhang, G.Lu, J.Qi, Y.Li, Y.He, X.Xu, J.Shi, C.W.Zhang, J.Yan, and G.F.Gao (2013).
Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4.
  Nat Struct Mol Biol, 20, 67-72.
PDB code: 4gjt
22902367 O.J.Harrison, J.Vendome, J.Brasch, X.Jin, S.Hong, P.S.Katsamba, G.Ahlsen, R.B.Troyanovsky, S.M.Troyanovsky, B.Honig, and L.Shapiro (2012).
Nectin ectodomain structures reveal a canonical adhesive interface.
  Nat Struct Mol Biol, 19, 906-915.
PDB codes: 4fmf 4fmk 4fn0 4fom 4fqp 4frw 4fs0
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.

 

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