PDBsum entry 4cc4

Cell invasion

PDB id: 4cc4

Contents

Protein chains

265 a.a.

68 a.a.

64 a.a.

Ligands

GOL ×5

PE4

SO4 ×2

PO4 ×2

Metals

_CL ×6

Waters ×280

PDB id:

4cc4

Name:

Cell invasion

Title:

Complex of inlc of listeria monocytogenes and human tuba c-terminal sh3 domain

Structure:

Inlc protein. Chain: a, e. Fragment: internalin domain, residues 35-297. Synonym: inlc, internalin, internalin b, internalin c. Engineered: yes. Mutation: yes. Dynamin-binding protein. Chain: b, d, f. Fragment: c-terminal sh3 domain of tuba, residues 1513-1577.

Source:

Listeria monocytogenes egd-e. Organism_taxid: 169963. Expressed in: escherichia coli. Expression_system_taxid: 511693. Homo sapiens. Human. Organism_taxid: 9606. Expression_system_variant: codonplus.

Resolution:

2.60Å R-factor: 0.199 R-free: 0.262

Authors:

L.Polle,L.Rigano,R.Julian,K.Ireton,W.-D.Schubert

Key ref:

L.Polle et al. (2014). Structural details of human tuba recruitment by InlC of Listeria monocytogenes elucidate bacterial cell-cell spreading. Structure, 22, 304-314. PubMed id: 24332715 DOI: 10.1016/j.str.2013.10.017

Date:

17-Oct-13 Release date: 30-Oct-13

Protein chains

P71451  (INLC_LISMG) -  Internalin C from Listeria monocytogenes serotype 1/2a (strain EGD / Mackaness)

Seq: 297 a.a.

Struc: 265 a.a.*

Protein chains

Q6XZF7  (DNMBP_HUMAN) -  Dynamin-binding protein from Homo sapiens

Seq: 1577 a.a.

Struc: 68 a.a.*

Protein chain

Q6XZF7  (DNMBP_HUMAN) -  Dynamin-binding protein from Homo sapiens

Seq: 1577 a.a.

Struc: 64 a.a.

* PDB and UniProt seqs differ at 9 residue positions (black crosses)

DOI no: 10.1016/j.str.2013.10.017

Structure 22:304-314 (2014)

PubMed id: 24332715

Structural details of human tuba recruitment by InlC of Listeria monocytogenes elucidate bacterial cell-cell spreading.

L.Polle, L.A.Rigano, R.Julian, K.Ireton, W.D.Schubert.

ABSTRACT

No abstract given.