PDBsum entry 4c3v

Hydrolase

PDB id: 4c3v

Contents

Protein chain

274 a.a.

Ligands

SO4 ×3

Metals

_CA

_NA ×3

Waters ×120

PDB id:

4c3v

Name:

Hydrolase

Title:

Extensive counter-ion interactions with subtilisin in aqueous medium, no cs soak

Structure:

Subtilisin carlsberg. Chain: a. Ec: 3.4.21.62

Source:

Bacillus licheniformis. Organism_taxid: 1402

Resolution:

2.26Å R-factor: 0.163 R-free: 0.226

Authors:

M.Cianci,J.Negroni,J.R.Helliwell,P.J.Halling

Key ref:

M.Cianci et al. Extensive counter-Ion interactions seen at the surface of subtilisin in an aqueous medium. Rsc adv, .

Date:

27-Aug-13 Release date: 20-Aug-14

Protein chain

P00780  (SUBC_BACLI) -  Subtilisin Carlsberg from Bacillus licheniformis

Seq: 379 a.a.

Struc: 274 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.4.21.62 - subtilisin.
• Reaction: Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.